P&S Signature

The P&S Signature Health Screen is a comprehensive and performance-focused diagnostic programme designed to deliver a detailed, clinically robust overview of your health. Positioned as a high-level preventive screen, it combines thorough clinical examination, advanced laboratory diagnostics, and cutting-edge imaging to identify early signs of disease while optimising overall health and performance.

At its core, the Signature screen is built around early detection and metabolic insight. Many conditions—including cardiovascular disease, hormonal imbalances, metabolic dysfunction, and certain cancers—can develop without obvious symptoms. This programme is designed to uncover those hidden risks early, enabling timely intervention and more precise, personalised health strategies.

The assessment begins with key clinical evaluations, including height, weight, BMI, respiratory and abdominal examinations, and a mental health review. These foundational checks provide an essential baseline, while gender-specific examinations—such as prostate and testicular, breast and pelvic, and rectal assessments—ensure a complete and tailored evaluation.

A comprehensive panel of blood testing provides in-depth analysis of internal health. Full haematology and biochemistry screens assess blood health, immune function, and metabolic balance, while kidney and liver function tests evaluate critical organ performance. Electrolytes, calcium, magnesium, and vitamin D levels help detect deficiencies affecting bone strength, neuromuscular function, and cardiovascular stability. Iron studies, vitamin B12, and folate testing identify anaemia and nutritional gaps, while muscle enzyme testing can reveal inflammation or tissue stress.

A key strength of the Signature programme is its enhanced metabolic and hormonal profiling. In addition to diabetes testing and cholesterol analysis, insulin levels and a metabolic hormone panel provide deeper insight into blood sugar regulation, metabolic efficiency, and early insulin resistance. Thyroid function testing further evaluates endocrine balance, while testosterone analysis and PSA prostate profiling support male health assessment.

Cardiovascular health is thoroughly evaluated through heart plaque markers, ECG exercise testing (ETT), and VO₂ max/CPET (cardiopulmonary exercise testing) analysis, offering a clear picture of cardiac function, fitness capacity, and long-term risk of heart disease.

Cancer screening is approached through a multi-layered strategy. Blood-based tumour markers, including CEA and CA19-9, alongside PSA testing and QFIT stool analysis for bowel cancer, help detect early warning signs. Trucheck Intelli multi-cancer screening enhances early detection across multiple cancer types, while a full-body MRI with a cancer focus provides advanced imaging to identify structural abnormalities at an early stage.

Further specialist testing adds depth and personalisation. Gut microbiome analysis offers insight into digestive health, immunity, and inflammation. Allergy profiling (ALEX 3) identifies sensitivities that may impact quality of life. Bone density and full body composition analysis assess musculoskeletal health and metabolic status, while ultrasound imaging of the abdomen and pelvis provides additional evaluation of internal organs.

Sexual health screening and broader hormonal assessments ensure reproductive and endocrine health are fully reviewed. 

The P&S Signature Health Screen provides a powerful, data-driven overview of your health, with a strong emphasis on metabolic function, hormonal balance, and early disease detection. It is ideally suited for individuals seeking a detailed, proactive approach to maintaining health, improving performance, and reducing long-term health risks.